Week 3 

Welcome to the third week of the course.

Here the focus will be to understand Who is the mastermind behind AMR?

What is Antimicrobial Resistance?
Have you heard of the term adaptation? What if i tell you that microorganisms gain resistance as a mechanism to find a way to survive and that it is a sign of struggle for existence?

Watch the video to know more.

Antimicrobial Resistance & Infections Part 1:
Let us understand Antimicrobial resistance with Tuberculosis as an example. 

Watch the video to know more.

Antimicrobial Resistance & Infections Part 2:
What are the causes of MDR TB?

What is the scenario in India with respect to MDR TB?

Watch the video to know more.

How does AMR Develop? Part1:

This video focuses on the various causes of antimicrobial resistance and selective pressure as one of the causes. 

Watch the video to know more. 

How does AMR develop? Part 2:

This video focuses on mutation and gene transfer as the causes of antimicrobial resistance and its subsequent spread. 

Watch the video to know how bacteria share and spread the characteristic of antimicrobial resistance.

How does AMR develop? Part 3:

This video focuses on inappropriate use of antibiotics as a major cause of antimicrobial resistance 

Watch the video to know more.

How does AMR Develop? Part 4:
Inadequate diagnostics, Hospital use and Agricultural use of antimicrobial agents has also promoted the surge of antimicrobial resistance. 

To know how, watch the video.

How does AMR Develop? Part 5:

Anthropogenic activities are contributing to the emergence of newer antimicrobial resistance strains and accelerating its spread. 

Watch the video to learn how.

Mechanisms of Resistance Part 1: 

In this video we will discuss about what the different defense strategies used by microorganisms which help them exhibit resistance to different antimicrobial agents. 

Mechanisms of Resistance Part 2: 

In this video we will discuss about the other two strategies used by microorganisms to exhibit resistance. 

Also let us summarize what we learnt and what is in store for the next week.

Reading material: 

https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance 

https://www.cdc.gov/drugresistance/about/how-resistance-happens.html 


For people from Biological Sciences: 

Causes of resistance: Michael CA, Dominey-Howes D and Labbate M (2014) The antimicrobial resistance crisis: causes, consequences, and management. Front. Public Health 2:145. doi: 10.3389/fpubh.2014.00145 https://www.frontiersin.org/articles/10.3389/fpubh.2014.00145/full 

Mechanisms of resistance:  Reygaert WC. An overview of the antimicrobial resistance mechanisms of bacteria. AIMS Microbiol. 2018 Jun 26;4(3):482-501. doi: 10.3934/microbiol.2018.3.482. PMID: 31294229; PMCID: PMC6604941. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604941/ 

Discussion forum:

Questions are true mark of learning... So please post your questions on this link: https://padlet.com/letusfightamr/discussion-forum-bqmo0p93piw1g0hb 

Activity 4: Mentimeter (Mandatory for certification)

Click on the link: https://www.menti.com/alo18fefibgu 

Mention three causes of AMR that surprised you the most. 

Assessment 3: (Mandatory for certification)

Click here to attempt the quiz: https://forms.gle/Pzn2m7Vvy8PsmMXx7 (10 points) 

Reflection Week 3: (Mandatory for Certification)

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Feedback Week 3: 

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